Acromegaly

Definition

• Q. What is acromegaly? Why is it called acromegaly?

Epidemiology

• Q

Etiology and Pathophysiology

• Q. What is the cause of acromegaly?
• Q. What happens if it occurs before closure of epiphysis?
• Q. Can acromegaly and gigantism exist togather?

Clinical manifestations

• Q. A 40-year-old male presents with progressively worsening headache and sweating for 6 months. On query he admitted history of clash with door and bystander, increasing size of shoes and ring. What is your diagnosis?
• Q. What are the presentations of acromegaly?
• Q. What are the signs of disease activity/active acromegaly?

Examinations

• Q. What are the examination findings of acromegaly?
  • Q. What are the causes of macroglossia?
  • Q. What are the causes of prominent supraorbital ridge?
  • Q. What are the causes of baggy eyelids?
• Q. What are the changes in the eyes in acromegaly?
• Q. What is the type of visual field defect in acromegaly?

Investigations

• Q. How would you investigate this patient?

Diagnosis

• Q. What are the differential diagnosis?
• A 40-year-old male presents with progressively worsening headache and sweating for 6 months. On query he admitted history of clash with door and bystander, increasing size of shoes and ring. What is your diagnosis? h64

Treatment

• Q. How would you treat acromegaly?
• Q. How will you assess response to therapy in acromegaly?

Complications

• Q. What are the complicatons of acromegaly?
• Q. What are the long term complications of acromegaly?
• Q. What are the causes of death in acromegaly?
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  • Q. What are the causes of hyperprolactinemia?