Definition

  • Define hepatitis. H4
  • What is HBsAg carrier? H34
  • What are the hepatotropic viruses? Hl
  • What is acute (fulminating) hepatic failure? Hl
    • Tell the classification of acute liver failure. Hl
  • What is fulminant hepatic failure? H106

Epidemiology

  • How many patients with hepatitis B virus infection develop chronicity? Hl

Etiology and Pathophysiology

  • What are the common causes of hepatitis? Hl
    • Name the drugs causing hepatitis. Hl
    • What are the viruses causing hepatitis? A, h7
    • What are the hepatotropic viruses? H8
  • Classify viral hepatitis./ What is the clinical classification of viral hepatitis? H9,hl
    • What are the genomic types of hepatitis viruses? Hl
    • What are the common causes of acute viralhepatitis? hl
    • Can HDV itself cause disease? H13
    • What is the mode of transmission of each virus? Hl
    • What is feco-oral route? Hl
    • How HBsAg is transmitted vertically? H35
    • Does hepatitis C virus cause acute hepatitis? H44
  • What are the causes of acute hepatitis? A
  • Which hepatitis viruses cause acute viral hepatitis? H10
  • What are the causes of chronic hepatitis? A
  • Which hepatitis viruses cause chronicity? Hl
  • What are the causes of acute liver failure? Hl

Clinical manifestations

  • What is the classical patterns of acute viral hepatitis? H16
  • What is the classical presentations of acute viral hepatitis? hl
  • What is the presentation of hepatitis C virus infection? H43
  • What are the features of FHF? Hl

Examinations

  • Q

Investigations

  • What investigations do you suggest in acute viral hepatitis? A, hl
  • What are the markers of HBV infection? A
  • Can you tell significance of antigen and antibody of HBV? H18
  • What are the markers of B virus replication? A
  • What are the components of liver function tests? H19
  • What is window period? Which marker will be found in this period? H20

Diagnosis

  • What are the points in favour of your diagnosis? hl
  • What are your differential diagnoses? A
  • Why is this not obstructive jaundice? A
  • Why is ths not CCF? Hl
  • Why not hemolytic jaundice? A
  • Why is this not liver abscess? Hl
    • When does jaundice occur in liver abscess? Hl
  • What history should be taken in acute viral hepatitis? A
  • A 15-year-old boy is diagnosed, he is suffering from acute viral hepatitis but HBsAg is negative. Which virus will you think next? H24
    • Why? H25
  • A 35-year-old lady is diagnosed, he is suffering from acute viral hepatitis but HBsAg is negative. Which virus will you think next? H27
    • Why? H28
    • Suppose this lady is pregnant, what is your concern? H29
  • A patient got admitted in the hospital with jaundice; suddenly he developed unconsciousness, what are the probable causes? H104

Treatment

  • How would you treat a patient with acute viral hepatitis? A, hl
  • What is the indication of hospital admission? Hl
  • What is the prognosis of acute viral hepatitis? A
  • What is the prognosis of acute hepatitis due to hepatitis A? hl
  • What is the prognosis of acute hepatitis due to hepatitis E? hl
  • How to treat chronic HBV infection? A
    • What are the drugs used to treat chronic hepatitis B? h32
    • Tell the indications of antiviral therapy. H33
    • How to treat a patient with incidental finding of positive HBsAg? A
    • How will you manage a case of HBsAg positive pregnancy? H36
  • What is the management of hepatitis C virus infection? H45
  • What are the principles of management of FHF? Hl
  • What are the principles of management of hepatic encephalopathy? Hl

Prevention

  • Against which viruses’ vaccine is available? Hl
  • How can you prevent HBV infection? H38
  • Can you tell about the route of administration, time schedule and booster dose, duration of protection of vaccine? H39
  • Tell Ab response after vaccination? H40
  • Which group of patient couldn’t achieve the protection? H41
  • What are the other causes of ineffectiveness of vaccine? H42

Complications

  • What are the complications of acute viral hepatitis? A, hl
  • What are the fates of hepatitis B virus infection? Hl

Features of different virus causing hepatitis a

  • Hepatitis A virus (HAV)
  • Hepatitis B virus (HBV)

Discussion on Weil’s Disease (Leptospirosis)

  • What is Weil’s disease? What is it’s mode of infection, clinical features, investigation and treatment? a
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