SCD

Definition and classification

• Why is it called combined degeneration? Hs96

Epidemiology

• Q

Etiology and Pathophysiology

• What are the causes of both pyramidal and dorsal column loss? Hs96
• What are the causes of dorsal column loss? Hs97
• Which tracts are involved in SCD of spinal cord? H37
• What is the cause of SCD? Hs97
• What are the causes of vitamin B₁₂ deficiency? Hs97
• What is the daily requirement of vitamin B₁₂? How long does it take to develop vitamin B₁₂ deficiency? Hs97
• Which type of anemia occur in vitamin B₁₂ deficiency? Hs97
• What is the cause of megaloblastic macrocytic anemia? Hs97

Clinical manifestations

• Please tell the neurological manifestations of vitamin B₁₂ deficiency? Hs97
• What are the non-neurological manifestations of vitamin B₁₂ deficiency? Hs97

Examinations

• Q

Investigations

• How will you investigate this patient? Hs97
• What are the expected findings in PBF? Hs97

Diagnosis

• What is your diagnosis? Hs96
• What are the differential diagnosis? Hs96

Treatment

• How would you treat this patient? Hs97
• What is the response of neurological lesion to vitamin B₁₂ therapy? Hs97

Complications

• Q