Definition and classification

  • What is MND? A, hl
  • What are the types of MND? A
  • What is fasciculation? A


  • What is the mean age of onset of MND? hl

Etiology and Pathophysiology

  • What are the causes of MND? A
  • What is the pathology of MND? A, hl
  • What are the patterns of involvement in MND? hl
  • What are the causes of fasciculation? a
    • What is the mechanism? A, hl
    • What is the difference between fasciculation and fibrillation of muscle? A
  • What is the clinical course of MND? hl

Clinical manifestations

  • Which features are strongly against the diagnosis of MND? hl
  • What are the causes of wasting of the small muscles of the hand? A
  • What are the neurological non-metastatic syndromes of malignancy? a


  • What are the signs of cerebellar lesion? H131


  • What investigations should be done in this case? A, hl
  • What changes occur in CSF in MND? hl


  • Why it is MND? A, hl
  • Why amytrophic lateral sclerosis? A, hl
  • Mention one common differential diagnosis to be excluded in such case. A
  • What are the differential diagnoses? A
  • Why is this not cervical spondylosis? hl
  • Could it be syringomyelia? A, hl
  • Why is this not myopathy? Hl
  • Why is this not peripheral neuropathy? hl
  • What are the differences between bulbar and pseudobulbar palsy? a


  • How to treat MND? A, hl
  • Is there any drug which improves survival? hl
  • What is the prognosis of MND? A, hl
    • Which type of MND have better prognosis? Hl
    • Which factors are associated with proper prognosis? hl


  • What are the causes of death in MND? Hl



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